Description: Ki-67 is a nuclear antigen is associated with cell proliferation and is found throughout the cell cycle including the G1, S, G2 and M phases but not the G0 phase. This characteristic makes Ki-67 an excellent marker for proliferating cells and is routinely used as a prognostic marker for cancers.
Catalog: VMAB013
Clone:
Species Reactivity: Cat and Dog
Source: Recombinant rabbit monoclonal
Antigen:
Cellular Location: Nuclear
Positive Control: Any actively proliferating cells such as skin, tonsil, or lymph node
References:
- Webster, J.D., Yuzbasiyan-Gurkan, V., Miller, R.A., Kaneene, J.B. and Kiupel, M. Cellular proliferation in canine cutaneous mast cell tumors: associations with c-KIT and its role in prognostication. Vet Pathol. 2007;44(3):298-303. [PMID: 17491070]
- Sledge, D.G., Webster, J. and Kiupel, M. Canine cutaneous mast cell tumors: A combined clinical and pathologic approach to diagnosis, prognosis, and treatment selection. Vet J. 2016;215:43-54. [PMID 27372911]
- Webster, J.D., Yuzbasiyan-Gurkan, V., Thamm, D.H., Hamilton, E. and Kiupel, M. Evaluation of prognostic markers for canine mast cell tumors treated with vinblastine and prednisone. BMC Vet Res. 2008;13:4-32. [PMID 18700956]