IFU
Description: This antibody recognizes the alpha and gamma isotopes of all muscle groups and can be used as a marker for skeletal, cardiac, and smooth muscle cells. Because this antibody does not stain neoplastic cells of non-muscle-derived tissues like carcinomas, melanomas, and lymphomas it is useful in identifying tumors of smooth muscle (leiomyomas and leiomyosarcomas) as well as skeletal muscle (rhabdomyomas and rhabdomyosarcomas).
Catalog: VMAB009
Clone: CHMP052
Species Reactivity: Cat and Dog
Source: Recombinant Mouse Monoclonal
Isotype: IgG1
Antigen: Synthetic peptide of human muscle actin
Cellular Location: Cytoplasmic
Positive Control: Muscle or sarcoma
References:
- Rangdaeng, S., and Truong, L.D. Comparative immunohistochemical staining for desmin and muscle-specific actin. A study of 576 cases. Am J Clin Pathol. 1991: 96(1):43-45. [PMID: 1712542]
- Barkalow, K., and Hartwig, J.H. Actin cytoskeleton. Setting the pace of cell movement. Curr Biol. 1995; 5(9):1000-2. [PMID: 8542272]
Bioinformatics:
Entrez Gene ID: 58, 59, 70
Gene Symbol: ACTA1 (Skeletal), ACTA2 (Smooth); ACTG2 (Smooth)
SwissProt: P62736, P63267, P68133