Cytokeratin 8

Cytokeratin 8

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IFU

DescriptionThis antibody is highly specific to cytokeratin 8 (CK8), which belongs to the type II (or basic) subfamily of high molecular weight cytokeratins and frequently exists in combination with cytokeratin 18 (CK18). In normal tissue, CK8 is primarily expressed in ductal and glandular epithelia, such as colon, stomach, small intestine, trachea, and esophagus, but not with squamous epithelium, skeletal muscle, or nerve cells. CK8 is also expressed in neoplastic epithelia and is present in the majority of adenocarcinomas and ductal carcinomas while absent in squamous cell carcinomas.

Catalog: VMAB014

Clone: CHMPXXX

Species Reactivity: Cat and Dog

Source: Recombinant Rabbit Monoclonal

Isotype: IgG

Antigen: Recombinant full-length human KRT8 protein

Cellular Location: Cytoplasmic

Positive Control: Colon, lung, and Skin

 

References: 

 

Bioinformatics

Entrez Gene ID: 3856
Gene Symbol: KRT8
SwissProt: P05787