
IFU
Description: This antibody is highly specific to cytokeratin 8 (CK8), which belongs to the type II (or basic) subfamily of high molecular weight cytokeratins and frequently exists in combination with cytokeratin 18 (CK18). In normal tissue, CK8 is primarily expressed in ductal and glandular epithelia, such as colon, stomach, small intestine, trachea, and esophagus, but not with squamous epithelium, skeletal muscle, or nerve cells. CK8 is also expressed in neoplastic epithelia and is present in the majority of adenocarcinomas and ductal carcinomas while absent in squamous cell carcinomas.
Catalog: VMAB014
Clone: CHMPXXX
Species Reactivity: Cat and Dog
Source: Recombinant Rabbit Monoclonal
Isotype: IgG
Antigen: Recombinant full-length human KRT8 protein
Cellular Location: Cytoplasmic
Positive Control: Colon, lung, and Skin
References:
Bioinformatics
Entrez Gene ID: 3856
Gene Symbol: KRT8
SwissProt: P05787